This includes alcoholic drinks and sleeping pills Anti-inflammatory medicines such as hydrocortisone, prednisolone, ACTH Non-steroidal anti-inflammatory drugs for example, aspirin or ibuprofen. Insulin or tablets taken for diabetes to control the blood sugar Antacids medicines used for indigestion Medicines used during surgical operations to relax muscles e. This is important if you go into hospital for an operation as your anaesthetist will want to know.
Drug information provided by: Micromedex Descriptions Quinapril and hydrochlorothiazide combination is used to treat high blood pressure hypertension.
High blood pressure adds to the workload of the heart and arteries.
If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure.
Hypertension may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled.
Quinapril is an angiotensin converting enzyme ACE inhibitor. It works by blocking a substance in the body that causes blood vessels to tighten. As a result, quinapril relaxes the blood vessels.
This lowers blood pressure and increases the supply of blood and oxygen to the heart. Hydrochlorothiazide is a diuretic water pill. It reduces the amount of water in the body by increasing the flow of urine which helps lower the blood pressure.
This medicine is available only with your doctor's prescription. This product is available in the following dosage forms: Tablet Before Using Portions of this document last updated: Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes.HPLC method for the simultaneous determination of Quinapril HCl (QUI) and Hydrochlorthiazide (HCTZ) in their combined pharmaceutical dosage form was developed.
The review of literature revealed that various analytical methods involving containing 50µg/ml QUI. Hydrochlorthiazide (HCTZ) standard stock solution: . Quinapril HCl/hydrochlorothiazide tablets are fixed-combination tablets that combine an angiotensin-converting enzyme (ACE) inhibitor, quinapril hydrochloride, and a thiazide diuretic, hydrochlorothiazide.
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Quinapril hydrochloride is a white to off-white amorphous powder that is freely soluble in aqueous solvents. Hydrochlorothiazide is chemically described as: 6-Chloro-3,4-dihydro-2H-1,2,4benzothiadiazinesulfonamide 1,1-dioxide.
Hydrochlorothiazide (HCTZ); quinapril may be substituted for the previously titrated individual components. Alternatively, a patient whose blood pressure is not adequately controlled with either quinapril or HCTZ monotherapy may be given the combination product, usually HCTZ mg and quinapril 10—20 mg PO once daily.
Accuretic is a fixed-combination tablet which combines the antihypertensive actions of an angiotensin-converting enzyme (ACE) inhibitor, quinapril HCl, and a diuretic, hydrochlorothiazide.
In clinical studies, administration of this combination produced greater reductions in blood pressure than the single agents given alone.